Nampt-IN-18 (Compound Q24) is an orally active NAMPT inhibitor with an IC50 of 8.0 nM against hNAMPT. Nampt-IN-18 inhibits NAMPT enzymatic activity. Nampt-IN-18 inhibits DNA synthesis and induces Apoptosis. Nampt-IN-18 exhibits anticancer activity against gastric cancer and colorectal cancer. Nampt-IN-18 can be used for the research of gastrointestinal cancers[1].
Molecular Weight:
475.56
Formula:
C27H30FN5O2
Target:
Apoptosis,DNA/RNA Synthesis,NAMPT
Application Notes:
MCE Product type: Reference compound
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