Autotaxin-IN-8, CAS [[3058084-21-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181931
Supplier Catalog Number:
HY-181931
Alternative Catalog Number:
MCE-HY-181931-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Autotaxin-IN-8 (Compound 14E) is an orally active Autotaxin inhibitor with an IC50 of 14.2 nM against hAutotaxin. Autotaxin-IN-8 inhibits Autotaxin activity, MAPK activation, LPAR1 and p-ERK1/2. Autotaxin-IN-8 reduces the phosphorylation levels of JNK and p38. Autotaxin-IN-8 decreases collagen deposition in a mouse model of pulmonary fibrosis. Autotaxin-IN-8 can be used in research related to pulmonary fibrosis[1].
