HDM2004 is a selective, orally active, blood-brain barrier-penetrant HPK1 inhibitor with an IC50 of 1.89 nM. HDM2004 exhibits anticancer activity against colon cancer. HDM2004 shows synergistic activity when combined with anti-PD-L1 in syngeneic mouse models. HDM2004 can be used for the research of colon cancer[1].
Molecular Weight:
485.62
CAS Number:
[2953016-30-1]
Formula:
C28H35N7O
Target:
MAP4K
Application Notes:
MCE Product type: Reference compound
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