ClpP activator-2, CAS [[3036751-71-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-181934
Supplier Catalog Number:
HY-181934
Alternative Catalog Number:
MCE-HY-181934-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
ClpP activator-2 (Compound GU18) is a ClpP activator with a Kd of 5.01 µM for HsClpP. ClpP activator-2 enhances the proteolytic activity of HsClpP and promotes the degradation of alpha-casein by HsClpP, with an EC50 of 1.09 µM. ClpP activator-2 induces the accumulation of mitochondrial reactive oxygen species (ROS), leading to damage to mitochondrial structure and function. ClpP activator-2 exhibits significant in vivo anti-multiple myeloma activity[1].
Molecular Weight:
483.31
CAS Number:
[3036751-71-7]
Formula:
C22H19Cl2F3N4O
Target:
ClpP,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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