XY25026 is an orally active LRH-1 inhibitor with an IC50 of 0.28 µM. XY25026 inhibits the proliferation of androgen receptor (AR)-positive prostate cancer cells, suppresses the expression of AR target genes KLK2 and KLK3, and inhibits tumor growth in xenograft models. XY25026 is applicable to the research of castration-resistant prostate cancer[1].
Molecular Weight:
470.60
Formula:
C30H34N2O3
Target:
Androgen Receptor,c-Myc,Orphan Nuclear Receptor
Application Notes:
MCE Product type: Reference compound
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