dHTC3 is a selective BRD4 molecular glue degrader. dHTC3 specifically recruits the first bromodomain of BRD4 to the E3 ubiquitin ligase complex (SCFFBXO3), thereby triggering the ubiquitination and degradation of BRD4[1].
Molecular Weight:
626.83
Formula:
C31H42N6O4S2
Target:
Epigenetic Reader Domain,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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