Anticancer agent 308 (compound 3s) is an AKT inhibitor with antitumor activity. Anticancer agent 308 reduces total AKT protein levels, thereby inhibiting the pro-survival PI3K/AKT signaling pathway. Anticancer agent 308 induces apoptosis, disrupts mitochondrial membrane potential, promotes reactive oxygen species (ROS) accumulation in mitochondria, and induces cell cycle arrest. Anticancer agent 308 inhibits cancer cell migration. Anticancer agent 308 is applicable to research related to breast cancer, lung adenocarcinoma, cervical cancer, prostate cancer, and hepatocellular carcinoma[1].
Molecular Weight:
265.27
Formula:
C15H11N3O2
Target:
Akt
Application Notes:
MCE Product type: Reference compound
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