ZLWH-67 is a beta-Carboline derivative and Antibacterial agent. ZLWH-67 inhibits DNA synthesis, suppresses biofilm formation, and increases reactive oxygen species (ROS) levels. ZLWH-67 exhibits potent in vitro antibacterial activity against MRSA (MIC = 0.5-4 µg/mL), S. epidermidis (MIC = 4 µg/mL), E. faecalis (MIC = 4-8 µg/mL), and S. pneumoniae (MIC = 16 µg/mL). ZLWH-67 displays anti-MRSA effects in murine skin and pneumonia infection models[1].
Molecular Weight:
428.44
CAS Number:
[3083425-49-1]
Formula:
C24H20N4O4
Target:
Bacterial,DNA/RNA Synthesis,Drug Derivative,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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