BLU-654 is an orally active antineoplastic agent and KIT inhibitor. BLU-654 is a highly selective inhibitor targeting wild-type KIT, PDGFRbeta, and KITV654A over most other kinases in the kinome. BLU-654 exerts sustained antineoplastic activity in KITV654A cell-derived xenograft mouse models. BLU-654 can be used in research related to Imatinib (HY-15463)-resistant gastrointestinal stromal tumors[1].
Molecular Weight:
429.49
CAS Number:
[2999638-62-7]
Formula:
C21H28FN7O2
Target:
c-Kit,PDGFR
Application Notes:
MCE Product type: Reference compound
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