PD-1/PD-L1-IN-61, CAS [[2983098-90-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-182047
Supplier Catalog Number:
HY-182047
Alternative Catalog Number:
MCE-HY-182047-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PD-1/PD-L1-IN-61 is a PD-1/PD-L1 interaction inhibitor with a human IC50 of 5.3 nM. PD-1/PD-L1-IN-61 embeds into the hydrophobic pocket at the PD-L1 dimer interface, stabilizing binding through hydrogen bonds and pi-pi stacking with PD-L1 residues. PD-1/PD-L1-IN-61 acts as an immune activator, enhances immune-killing activity of peripheral blood mononuclear cells against cancer cells, restores T-cell immune function, and promotes IFN-gamma secretion. PD-1/PD-L1-IN-61 can be used for the research of triple-negative breast cancer[1].
Molecular Weight:
776.83
CAS Number:
[2983098-90-2]
Formula:
C42H44N6O9
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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