Anticancer agent 310 is an antitumor agent. Anticancer agent 310 releases nitric oxide to induce mitochondrial ROS burst, triggers mitochondrial dysfunction and activates the Bax/Bcl-2-Cyt c-Caspase-9/Caspase-3 apoptotic pathway. Anticancer agent 310 also reduces the levels of SHMT2 and MTHFD2, decreases the ratios of NADPH/NADP+ and GSH/GSSG, thereby disrupting redox homeostasis and exacerbating intracellular ROS accumulation. Anticancer agent 310 can be used in research related to gastric cancer[1].
Molecular Weight:
684.71
Formula:
C33H36N2O12S
Target:
Apoptosis,Bcl-2 Family,Caspase,Cytochrome P450,Methylenetetrahydrofolate Dehydrogenase (MTHFD),Reactive Oxygen Species (ROS),SHMT
Application Notes:
MCE Product type: Reference compound
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