SGK1-IN-7 is a blood-brain barrier-permeable SGK1 inhibitor with an IC50 of 0.72 µM. SGK1-IN-7 reduces the phosphorylation level of TAU protein at the Ser396 and Ser214 epitopes. SGK1-IN-7 antagonizes the toxicity induced by Okadaic acid (HY-N6785). SGK1-IN-7 can be used in the research of Alzheimers disease[1].
Molecular Weight:
385.25
CAS Number:
[3109982-58-0]
Formula:
C19H14Cl2N4O
Target:
SGK,Tau Protein
Application Notes:
MCE Product type: Reference compound
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