MLKL ligand-2 is a mixed lineage kinase domain-like pseudokinase (MLKL) PROTAC ligand with a KD of 9.408 µM. MLKL ligand-2 forms hydrogen bond networks and hydrophobic interactions with specific MLKL residues, and stabilizes MLKL in hepatic cells. MLKL ligand-2 can be used to synthesize PROTAC MLKL Degrader-3 (HY-182343)[1].
Molecular Weight:
658.67
Formula:
C30H30F4N8O3S
Target:
Ligands for Target Protein for PROTAC,Mixed Lineage Kinase
Application Notes:
MCE Product type: Reference compound
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