FXR DUBTAC IN-1, CAS [[3081876-96-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-182350
Supplier Catalog Number:
HY-182350
Alternative Catalog Number:
MCE-HY-182350-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
FXR DUBTAC IN-1 (compound D11) is a deubiquitinase-targeting chimeric molecule (DUBTAC) that targets FXR, with a Ka value of 2.12e-5 M for FXR. FXR DUBTAC IN-1 recruits the deubiquitinase OTUB1, binds to OTUB1 and forms a ternary complex with FXR, reduces the polyubiquitination level of FXR, prevents FXR degradation via the ubiquitin-proteasome pathway, and elevates the protein level of FXR. FXR DUBTAC IN-1 can be used in the research of cholestatic liver injury[1].
Molecular Weight:
751.01
CAS Number:
[3081876-96-9]
Formula:
C43H66N4O7
Target:
Deubiquitinase,DUBTACs
Application Notes:
MCE Product type: Reference compound
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