PAK1-IN-3 is a PAK1 inhibitor with an IC50 of 10 nM, an IC50 of 20 nM against PAK2, and an IC50 of 1079 nM against hERG potassium channels. PAK1-IN-3 forms a salt bridge with Asp106 in PAK1 via a properly positioned tertiary amine. PAK1-IN-3 inhibits PAK2 and hERG potassium channels[1].
Molecular Weight:
535.04
Formula:
C27H31ClN8O2
Target:
PAK,Potassium Channel
Application Notes:
MCE Product type: Reference compound1
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