AGI-25696 is an orally active ethionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 97 nM. AGI-25696 reduces intracellular SAM levels in cancer cells. AGI-25696 inhibits tumor growth in mice bearing subcutaneous KP4 MTAP-null pancreatic xenografts. AGI-25696 can be used for the research of mtap-deleted pancreatic cancer[1].
Molecular Weight:
428.48
CAS Number:
[2201065-84-9]
Formula:
C28H20N4O
Target:
Methionine Adenosyltransferase (MAT)
Application Notes:
MCE Product type: Reference compound
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