AL-38022A is a potent and selective 5-HT2 receptor agonist (Ki 2.2 nM), but a significantly lower (>100-fold less) affinity for other 5-HT receptors. AL-38022A potently stimulates functional responses via 5-HT2 receptor subtypes including [Ca2+]i mobilization and tissue contractions with apparently similar potencies and intrinsic activities. AL-38022A fully generalizes to the ()-1-(2,5-dimethoxy 4-methylphenyl)-2-aminopropane hydrochloride (DOM) stimulus in drug discrimination paradigms. AL-38022A can be used for the glaucoma research[1].
Molecular Weight:
231.29
CAS Number:
[478132-11-5]
Formula:
C13H17N3O
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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