NSC-2888 is a Rho kinase II (ROCK-II) inhibitor with an IC50 of 8.4 nM against human targets. NSC-2888 inhibits enzymatic activity by binding to active site amino acids via hydrogen bonds and hydrophobic interactions. NSC-2888 induces relaxation of pre-contracted rat aortic strips. NSC-2888 can be used in research related to hypertension[1].
Molecular Weight:
210.36
CAS Number:
[5335-14-8]
Formula:
C8H18O2S2
Target:
ROCK
Application Notes:
MCE Product type: Reference compound
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