LP-935001 is a Notum carboxylesterase inhibitor with an IC50 of 0.4 nM.LP-935001 prevents palmitoleate group removal from Wnt proteins, restores Wnt/beta-catenin signaling.LP-935001 enhances cortical bone thickness in rodent models.LP-935001 can be used for the research of bone loss/nonvertebral fractures[1].
Molecular Weight:
282.72
CAS Number:
[1875037-24-3]
Formula:
C13H8ClFO2S
Target:
Carboxylesterase (CES),Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
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