K811 is an orally active ASK1 inhibitor with an IC50 of 6 nM. K811 inhibits glial cell activation in the lumbar spinal cord of SOD1G93A transgenic mice. K811 extends the survival of SOD1G93A transgenic mice, a mouse model of amyotrophic lateral sclerosis. K811 can be used in studies related to amyotrophic lateral sclerosis[1].
Molecular Weight:
510.54
CAS Number:
[1355228-38-4]
Formula:
C29H26N4O5
Application Notes:
MCE Product type: Reference compound
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