LY3358966 is an orally active sodium-dependent phosphate cotransporter 2b (NPT2b) inhibitor with a human IC50 of 32.4 nM, mouse IC50 of 43.9 nM, and rat of IC50 26.8 nM. LY3358966 inhibits NPT2b-mediated intestinal phosphate transport, decreases acute phosphate uptake into plasma, and increases fecal phosphate excretion. LY3358966 can be used for the research of renal disease[1].
Molecular Weight:
801.94
CAS Number:
[2187395-66-8]
Formula:
C43H49F2N5O6S
Target:
Sodium Channel
Application Notes:
MCE Product type: Reference compound1
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