SBI-5844 (SBI-1275844) is a eIF4F complex inhibitor and antiviral agent. SBI-5844 disrupts the assembly of the eIF4F complex and blocks the interaction between eIF4E and eIF4G. SBI-5844 inhibits the synthesis of HCoV-OC43 nucleocapsid protein and reduces the levels of HCoV-OC43 RNA and total protein. SBI-5844 can be used in studies related to human coronavirus OC43 (HCoV-OC43) infection[1].
Molecular Weight:
335.44
CAS Number:
[832680-32-7]
Formula:
C22H25NO2
Target:
Eukaryotic Initiation Factor (eIF),SARS-CoV
Application Notes:
MCE Product type: Reference compound1
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