UT-105 is an orally active androgen receptor (AR) degrader. UT-105 binds to the N-terminal domain of AR and promotes its degradation. UT-105 inhibits the growth of enzalutamide-resistant breast cancer xenografts and reduces tumor cell proliferation. UT-105 can be used in the research of estrogen receptor-positive breast cancer[1].
Molecular Weight:
364.28
CAS Number:
[2388536-21-6]
Formula:
C15H11F3N6O2
Target:
Androgen Receptor
Application Notes:
MCE Product type: Reference compound1
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