BMS-357075 is a pan-CDK inhibitor with CDK1 IC50 18 nM, CDK2 IC50 3 nM, CDK4 IC50 26 nM. BMS-357075 induces cytotoxicity in human ovarian cancer A2780 cells. BMS-357075 exhibits anticancer activity in mice against P388 murine leukemia. BMS-357075 can be used for the research of leukemia[1].
Molecular Weight:
461.64
CAS Number:
[350509-99-8]
Formula:
C22H31N5O2S2
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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