NL-26 is a Topoisomerase I inhibitor. NL-26 stabilizes the covalent Topoisomerase I (Topo I)-DNA complex, prevents DNA religation and triggers the DNA damage response. NL-26 induces G2/M cell cycle arrest and apoptosis in cancer cells. NL-26 can be used for the research of colorectal cancer[1].
Molecular Weight:
377.39
Formula:
C21H19N3O4
Target:
Apoptosis,DNA/RNA Synthesis,Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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