JNUTS013 is a NLRP3 inflammasome inhibitor. JNUTS013 promotes proteasome-dependent degradation of NLRP3 and inhibits the release of downstream cytokines. JNUTS013 downregulates the expression of inflammation-related proteins including iNOS and COX-2. JNUTS013 exhibits anti-inflammatory activity and can be used in the research of inflammatory diseases[1].
Molecular Weight:
358.39
CAS Number:
[2763983-45-3]
Formula:
C20H22O6
Target:
COX,NO Synthase,NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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