Anticancer agent 313 is a MetAP2 inhibitor with an IC50 of 4.11 µM. Anticancer agent 313 activates the transcription factor ATF4 via a non-canonical mTORC1-dependent pathway. Anticancer agent 313 inhibits cancer cell proliferation. Anticancer agent 313 is applicable to the research of breast cancer and pancreatic cancer[1].
Molecular Weight:
346.50
Formula:
C18H26N2O3Si
Target:
MetAP
Application Notes:
MCE Product type: Reference compound
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