VEGFR2-IN-86 is a dual VEGFR2/CDK2 inhibitor, with an IC50 of 0.06 µM against VEGFR2 and an IC50 of 0.78 µM against CDK2. VEGFR2-IN-86 induces G-phase cell cycle arrest, reduces colony-forming ability and tumor cell migration capacity, and exerts antiproliferative activity in cancer cells. VEGFR2-IN-86 can be used for the research of breast cancer and prostate cancer[1].
Molecular Weight:
329.35
Formula:
C20H15N3O2
Target:
CDK,VEGFR
Application Notes:
MCE Product type: Reference compound
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