Len-604 is a FGFR inhibitor with IC50 values of 9.71 nM, 9.93 nM, 29.80 nM and 14.48 nM against FGFR4, FGFR1, FGFR2 and FGFR3, respectively. Len-604 reduces the phosphorylation levels of FGFR4 and ERK, and induces DNA damage and apoptosis in cancer cells. Len-604 is applicable to research related to liver cancer[1].
Molecular Weight:
880.17
Formula:
C30H33ClN8O9Pt
Target:
Apoptosis,DNA/RNA Synthesis,EGFR,ERK
Application Notes:
MCE Product type: Reference compound
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