Gal-dMor-Gem is a selective senescent cell scavenger, Apoptosis inducer, and a prodrug of Gemcitabine (HY-17026). Gal-dMor-Gem releases Gemcitabine upon activation by Esterases and beta-gal. Gal-dMor-Gem reduces SA-beta-gal, preferentially induces apoptosis in senescent cells, regulates apoptosis-related proteins, accumulates in senescent tissues, and ameliorates senescence-related organ phenotypes. Gal-dMor-Gem is applicable to research on chemotherapy-induced senescence[1].
Molecular Weight:
939.91
Formula:
C42H55F2N5O17
Target:
Apoptosis,Glycosidase
Application Notes:
MCE Product type: Reference compound
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