SD-965 is a selective STAT3 PROTAC degrader with a DC50 of 0.14 µM. SD-965 promotes the ubiquitination and degradation of STAT3. SD-965 induces rapid, complete and persistent depletion of STAT3 protein. SD-965 induces tumor regression in mouse xenograft models of leukemia and lymphoma[1].
Molecular Weight:
1213.21
CAS Number:
[3054394-56-5]
Formula:
C56H65N10O17PS
Target:
PROTACs,STAT
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted