Topoisomerase I/II-IN-9 is a topoisomerase I/II inhibitor (IC50cGAS-STING pathway and promotes the accumulation of cytoplasmic double-stranded DNA. This further drives the production of type I interferons, CCL5, CXCL10 and interferon-stimulated genes, and induces anti-tumor immune responses in vivo. Topoisomerase I/II-IN-9 can be applied to the research of related diseases such as triple-negative breast cancer, colorectal cancer and gastric cancer[1].
Molecular Weight:
761.72
Formula:
C35H37F6N3OPRu
Target:
DNA/RNA Synthesis,Topoisomerase
Application Notes:
MCE Product type: Reference compound
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