DDB1 ligand-1 is a DNA damage-binding protein 1 (DDB1) ligand. DDB1 ligand-1 binds to a unique pocket on the beta propeller C (BPC) domain of DDB1, induces conformational changes, and blocks the canonical DCAF/HBx peptide binding site of DDB1. DDB1 ligand-1 engages full-length DDB1 in cellular settings and supports PROTAC development research[1].
Molecular Weight:
590.62
Formula:
C32H32F2N4O5
Target:
Ligands for E3 Ligase
Application Notes:
MCE Product type: Reference compound
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