GRK2 modulator 1, CAS [[2234900-83-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-183057
Supplier Catalog Number:
HY-183057
Alternative Catalog Number:
MCE-HY-183057-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
GRK2 modulator 1 is an orally active, brain-penetrant and selective GRK2 modulator. GRK2 modulator 1 enhances the active, non-phosphorylated GRK2 and prevents mitochondrial GRK2 and TOMM6 aggregation. GRK2 modulator 1 enhances the non-amyloidogenic processing of APP and prevent PHF-tau, neurodegeneration, and neuronal loss. GRK2 modulator 1 decreases the senescence marker, UPAR, reduces the Alzheimer disease (AD)-related mortality, and prolongs survival. GRK2 modulator 1 exerts neuroprotection by inhibiting HDAC6, and counteracts age-related cardiac dysfunction. GRK2 modulator 1 can be used for research on AD[1].
Molecular Weight:
363.36
CAS Number:
[2234900-83-3]
Formula:
C21H17NO5
Target:
G Protein-coupled Receptor Kinase (GRK),HDAC
Application Notes:
MCE Product type: Reference compound
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