COX-2-IN-66 is a cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 8.43 µM. COX-2-IN-66 reduces release of pro-inflammatory cytokines IL-6 and TNF-alpha. COX-2-IN-66 exhibits acceptable cellular tolerability, with cytokine-modulating concentrations remaining below its cytotoxic threshold. COX-2-IN-66 can be used for the research of inflammation[1].
Molecular Weight:
345.43
Formula:
C23H23NO2
Target:
COX,Interleukin Related,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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