Antibacterial agent 343 (Compound 47) is an Antibacterial agent. Antibacterial agent 343 binds to the allosteric site of PBP2a to open its active site. Antibacterial agent 343 disrupts bacterial cell membranes, leading to protein leakage. Antibacterial agent 343 interacts with DNA and inhibits replication and transcription. Antibacterial agent 343 induces ROS accumulation. Antibacterial agent 343 exhibits antibacterial activity against MRSA, Staphylococcus aureus, and Enterococcus faecalis. Antibacterial agent 343 can be used for the research of methicillin-resistant Staphylococcus aureus infections[1].
Molecular Weight:
750.80
Formula:
C33H34N8O9S2
Target:
Bacterial,DNA Alkylator/Crosslinker,DNA/RNA Synthesis,Penicillin-binding protein (PBP),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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