MI 63 is an activator for p53, by targeting the MDM2 (Ki is 3 nM). MI 63 inhibits the proliferation of embryonic and alveolar rhabdomyosarcoma (ERMS and ARMS) cells (IC50 is 0.58 µM in RH36 cells), and induces apoptosis in ERMS and ARMS[1].
Molecular Weight:
577.52
CAS Number:
[908027-21-4]
Formula:
C29H35Cl2FN4O3
Target:
MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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