DOV-102,677, CAS [[410074-75-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-18332B
Supplier Catalog Number:
HY-18332B
Alternative Catalog Number:
MCE-HY-18332B-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
DOV-102,677 is an orally sctive triple monoamine neurotransmitter reuptake inhibitor that simultaneously inhibits the dopamine (DAT) (IC50 = 129 nM, Ki = 222 nM), norepinephrine (NET) (IC50 = 103 nM, Ki = 1030 nM), and serotonin (SERT) (IC50 = 133 nM, Ki = 740 nM) transporters. DOV-102,677 demonstrated significant antidepressant-like activity and sensory-motor gating regulatory effects in mouse experiments. DOV-102,677 can be used for research on depression[1].
