DOV-216,303 (Free Base) is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats[1][2].
Molecular Weight:
228.12
Purity:
98.17
CAS Number:
[66504-40-3]
Formula:
C11H11Cl2N
Target:
Dopamine Transporter,Serotonin Transporter
Application Notes:
MCE Product type: Reference compound
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