ALK-IN-37 is an orally active type I1/2 allosteric inhibitor of anaplastic lymphoma kinase (ALK) with an IC50 of 9.58 nM. ALK-IN-37 induces cell apoptosis, inhibits colony formation, suppresses cell migration, and exerts antiproliferative effects in cancer cells overexpressing ALK. ALK-IN-37 can be used in research related to non-small cell lung cancer[1].
Molecular Weight:
344.37
Formula:
C19H16N6O
Target:
Anaplastic lymphoma kinase (ALK),Apoptosis
Application Notes:
MCE Product type: Reference compound
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