Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis[1][2].
Molecular Weight:
514.95
Purity:
99.80
CAS Number:
[1228035-68-4]
Formula:
C26H27ClN2O7
Target:
Topoisomerase
Application Notes:
MCE Product type: Reference compound
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