mCPX is a prodrug of the antifungal agent Ciclopirox olamine (CPX) (HY-B0450A). CPX exhibits bacteriostatic and iron-chelating activities, while mCPX enhances the iron stability of CPX. mCPX inherits the core mechanism pathway of CPX and can induce EBV lytic reactivation in EBV+ gastric cancer cells via the hypoxia pathway (HIF-1alpha). mCPX is applicable to research related to EBV-positive gastric cancer[1].
Molecular Weight:
249.31
CAS Number:
[1351572-56-9]
Formula:
C14H19NO3
Target:
Drug Intermediate,EBV,HIF/HIF Prolyl-Hydroxylase
Application Notes:
MCE Product type: Reference compound
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