AUBE00 is an orally active, selective cyclic peptide pan-KRAS inhibitor. AUBE00 selectively binds to the OFF state of KRAS. AUBE00 exhibits anticancer activity against RAS wild-type colorectal cancer. The combination of AUBE00 with Cetuximab (HY-P9905) produces a synergistic antiproliferative effect[1].
Molecular Weight:
1553.77
CAS Number:
[2874214-01-2]
Formula:
C78H110F6N12O14
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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