G721-0377 is a CHI3L1 modulator with a human Kd value of 45 µM. G721-0377 binds to CHI3L1 and modulates downstream signaling pathways. G721-0377 suppresses CHI3L1-induced NF-kappaB activation, decreases secretion of CHI3L1 and IL-6. G721-0377 can be used for the research of Alzheimers disease[1].
Molecular Weight:
455.53
CAS Number:
[946336-44-3]
Formula:
C22H25N5O4S
Target:
Glycosidase,Interleukin Related,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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