Mcl-1-IN-22 is a selective Mcl-1 inhibitor with a Ki of 0.015 µM. Mcl-1-IN-22 binds selectively to Mcl-1, disrupts the Mcl-1/Bak complex to release free Bak, triggering intrinsic apoptosis. Mcl-1-IN-22 can be used for the research of ovarian cancer[1].
Molecular Weight:
552.49
Formula:
C30H31Cl2N3O3
Target:
Apoptosis,Bcl-2 Family
Application Notes:
MCE Product type: Reference compound
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