Mcl-1-IN-22 hydrochloride is a tetrahydro-beta-carboline-based Mcl-1 inhibitor with a Ki of 0.015 µM. Mcl-1-IN-22 hydrochloride shows antitumor activity, induces apoptosis and produces synergistic antitumor effects in combination with Cisplatin (HY-17394) and Paclitaxel (HY-B0015). Mcl-1-IN-22 hydrochloride can be used for the research of cancer, such as ovarian cancer[1].
Molecular Weight:
554.51
Formula:
C30H33Cl2N3O3
Target:
Apoptosis,Bcl-2 Family
Application Notes:
MCE Product type: Reference compound
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