PM54 is an antitumor agent with activity across multiple cancer types. PM54 acts as a transcription and WNT/beta-catenin signaling pathway inhibitor. PM54 suppresses oncogenic transcriptional programs, and key malignant pathways, while inducing DNA double-strand breaks, S-phase cell cycle arrest and apoptosis. PM54 enhances innate immune recognition, remodels the tumor microenvironment. PM54 exhibits antitumor activity as monotherapy or in combination in xenograft models. PM54 is applicable to research on various cancers and advanced solid tumors[1][2][3].
Molecular Weight:
785.86
CAS Number:
[2248127-86-6]
Formula:
C41H43N3O11S
Target:
Apoptosis,c-Myc,mTOR,Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
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