15-PGDH-IN-5, CAS [[1714984-32-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-183651
Supplier Catalog Number:
HY-183651
Alternative Catalog Number:
MCE-HY-183651-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
15-PGDH-IN-5 (compound 5) is a sulfoxide-derived 15-PGDH inhibitor. 15-PGDH-IN-5 exhibits higher metabolic stability and superior in vivo exposure compared with the lead compound SW033291 (HY-16968). 15-PGDH-IN-5 inhibits the irreversible oxidative catabolism of PGE2 by 15-PGDH, thereby enhancing the tissue-specific bioavailability of endogenous PGE2. 15-PGDH-IN-5 exerts anti-inflammatory effects and accelerates tissue repair and regeneration, and it is used in studies on tissue injury and fibrosis-related diseases such as inflammatory bowel disease and idiopathic pulmonary fibrosis[1].
Molecular Weight:
431.60
CAS Number:
[1714984-32-3]
Formula:
C19H21N5OS3
Target:
15-PGDH
Application Notes:
MCE Product type: Reference compound
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