YSA64 is an orally active RBM39-targeting molecular glue. YSA64 promotes degradation via formation of a DCAF15/DDB1 ternary complex, dependent on Cullin-RING E3 ligase and proteasome activity. YSA64 can be used for the research of acute myeloid leukemia and Ewing sarcoma[1].
Molecular Weight:
460.55
Formula:
C25H24N4O3S
Target:
Molecular Glues
Application Notes:
MCE Product type: Reference compound
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