CDK4/6-IN-28, CAS [[3110098-09-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-183771
Supplier Catalog Number:
HY-183771
Alternative Catalog Number:
MCE-HY-183771-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
CDK4/6-IN-28 is a potent, orally active, and selective CDK4/6 inhibitor IC50 values of 14.02 and 10.03 nM, respectively. CDK4/6-IN-28 inhibits breast cancer cell colony formation, migration, and proliferation. CDK4/6-IN-28 induces G1-phase cell cycle arrest and apoptosis in breast cancer cells. CDK4/6-IN-28 exhibits tumor inhibitory activity in breast cancer xenograft mouse models. CDK4/6-IN-28 can be used for the research of breast cancer[1].
Molecular Weight:
427.54
CAS Number:
[3110098-09-1]
Formula:
C25H29N7
Target:
Apoptosis,Bcl-2 Family,Caspase,CDK,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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